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©The Author(s) 2021.
World J Gastroenterol. Jun 14, 2021; 27(22): 2944-2962
Published online Jun 14, 2021. doi: 10.3748/wjg.v27.i22.2944
Published online Jun 14, 2021. doi: 10.3748/wjg.v27.i22.2944
Table 2 Classification of the severity of liver injury in terms of the adverse outcome of coronavirus disease
| Ref. | Date | Cohort | The severity of liver injury | How the ULN was defined | ||
| Normal/mild (< 2 times ULN) | moderate (2-5 times ULN) | Severe (> 5 times ULN) | ||||
| Phipps et al[129] | March 8, 2020-April 14, 2020 | 2273 | 1784 (78.5) | 344 (15.1) | 145 (6.4) | ALT = 50 U/L |
| Mendizabal et al[130] | April 15, 2020-July 31, 2020 | 1611 | 322 (84.7) | 185 (11.5) | 61 (3.8) | ALT (the reference value of different institutions) |
| Hundt et al[131] | March 14, 2020-April, 2020 | 1753 | 1123 (64.1) | 408 (23.3) | 222 (12.7) | ALT = 34 U / L |
| Yip et al[132] | January 23, 2020-May 1, 2020 | 816 | 635 (77.8) | 141 (17.3) | 40 (4.9) | ALT = 40 U / L |
- Citation: Zhu DD, Tan XM, Lu LQ, Yu SJ, Jian RL, Liang XF, Liao YX, Fan W, Barbier-Torres L, Yang A, Yang HP, Liu T. Interplay between nuclear factor erythroid 2-related factor 2 and inflammatory mediators in COVID-19-related liver injury. World J Gastroenterol 2021; 27(22): 2944-2962
- URL: https://www.wjgnet.com/1007-9327/full/v27/i22/2944.htm
- DOI: https://dx.doi.org/10.3748/wjg.v27.i22.2944