Copyright
©The Author(s) 2021.
World J Gastroenterol. Jun 14, 2021; 27(22): 2944-2962
Published online Jun 14, 2021. doi: 10.3748/wjg.v27.i22.2944
Published online Jun 14, 2021. doi: 10.3748/wjg.v27.i22.2944
Ref. | Total number of patients | Proportion of liver injury, (%) | Proportions of pre-existing liver diseases, n (%) | Others |
Guan et al[87] | 1099 | Elevated AST 168/757 (22.2); Elevated ALT 158/741 (21.3); Elevated TB 76/722 (10.5) | 23 (2.1) | |
Lian et al[56] | 465 | 61 (13.1) | 19 (4.1) | Liver injury was the most common complication among these patients |
Chen et al[88] | 503 | 301 (69.8) | NA | Liver damage is an independent prognostic factor of COVID-19 |
Jin et al[55] | 651 | 64 (9.8) | 25 (3.8) | |
Xie et al[89] | 79 | Elevated ALT (31.6); Elevated AST (35.4); Elevated TB (5.1) | NA | COVID-19 with liver injury in non-ICU hospitalized patients was common |
Wang et al[90] | 293 | 19 (6.5) | 12 (4.1) | Compared with the survival group, the non-survival group was more prone to complications of acute liver injury |
Chen et al[91] | 274 | Elevated AST 84 (31) | 11 (4) | The frequency of liver injury in the deceased patients was significantly higher than that in the recovered patients |
Yu et al[54] | 1633 | Elevated ALT 298/1445 (20.6); Elevated AST 303/1445 (21.0) | 38 (2.3) | Severe patients are more likely to have liver injury than mild patients |
- Citation: Zhu DD, Tan XM, Lu LQ, Yu SJ, Jian RL, Liang XF, Liao YX, Fan W, Barbier-Torres L, Yang A, Yang HP, Liu T. Interplay between nuclear factor erythroid 2-related factor 2 and inflammatory mediators in COVID-19-related liver injury. World J Gastroenterol 2021; 27(22): 2944-2962
- URL: https://www.wjgnet.com/1007-9327/full/v27/i22/2944.htm
- DOI: https://dx.doi.org/10.3748/wjg.v27.i22.2944