Survival-associated alternative splicing events interact with the immune microenvironment in stomach adenocarcinoma

Figure 1 Overview of alternative splicing events profiling in stomach adenocarcinoma. A: The flow chart for identification of overall survival (OS)-related alternative splicing (AS) signatures in stomach adenocarcinoma (STAD); B: Schematic diagram of seven splicing modes; C: UpSet plot of different types of AS events in STAD; D: Volcano plot of OS-related AS events in STAD. Upregulated OS-related AS events are indicated by red points and downregulated OS-related AS events by green points. TCGA: The Cancer Genome Atlas; KEGG: Kyoto Encyclopedia of Genes and Genomes; GO: Gene Ontology; PPI: Protein-protein interaction; ES: Exon skip; AP: Alternate promoters; AT: Alternate terminators; AA: Alternate acceptors; AD: Alternate donors; RI: Retained introns; ME: Exclusive exons.