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Copyright ©The Author(s) 2021.
World J Gastroenterol. Jun 7, 2021; 27(21): 2795-2817
Published online Jun 7, 2021. doi: 10.3748/wjg.v27.i21.2795
Table 17 Summary of evidence from population-based studies for factors potentially associated with constipation
Category
Factor
Association with constipation
DemographicAgeConflicting data, probably only > 70 yr
Female genderAssociated
Income levelConflicting data, probably country specific
Educational levelConflicting data, probably country specific
Residential locationAssociated
Work statusConflicting data
Marital statusConflicting data
EthnicityPossible association
LifestylePhysical activityAssociated
Fibre No evidence for low fibre
FluidPossible association
SmokingConflicting data
AlcoholNo clear evidence
CoffeeNo association
Health-relatedSelf-rated healthAssociated
ObesityConflicting data
DepressionAssociated
AnorectalAssociated – haemorrhoids and other conditions
GastrointestinalAssociated
NeurologicalAssociated – MS, Parkinson’s disease
EndocrineAssociated - diabetes
CardiovascularAssociated
MusculoskeletalAssociated
SurgeryAssociated – gynaecological, anorectal, abdominal
No. of medicationsPossible association
NSAIDsAssociated
AspirinAssociated
Other drugsPossible association