Copyright
©The Author(s) 2021.
World J Gastroenterol. Jun 7, 2021; 27(21): 2710-2726
Published online Jun 7, 2021. doi: 10.3748/wjg.v27.i21.2710
Published online Jun 7, 2021. doi: 10.3748/wjg.v27.i21.2710
Table 3 Main genetic alterations detectable in other pancreatic tumors
Type of pancreatic lesion | Genetic alteration | Reported frequency (%) | Type of alterations | Role in clinical practice |
SPN | CTNNB1 | 90-100 | Point mutations | Diagnostic |
PanNET | MEN1 | 70 | Point mutations/LOH | Diagnostic/prognostic |
VHL | 25 | Point mutations/LOH | Diagnostic | |
AAC | CTNNB1 | 5-25 | Point mutationsLOF | Diagnostic |
MSI | 5-15 | LOF | Predictive? |
- Citation: Visani M, Acquaviva G, De Leo A, Sanza V, Merlo L, Maloberti T, Brandes AA, Franceschi E, Di Battista M, Masetti M, Jovine E, Fiorino S, Pession A, Tallini G, de Biase D. Molecular alterations in pancreatic tumors. World J Gastroenterol 2021; 27(21): 2710-2726
- URL: https://www.wjgnet.com/1007-9327/full/v27/i21/2710.htm
- DOI: https://dx.doi.org/10.3748/wjg.v27.i21.2710