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©The Author(s) 2021.
World J Gastroenterol. May 28, 2021; 27(20): 2586-2602
Published online May 28, 2021. doi: 10.3748/wjg.v27.i20.2586
Published online May 28, 2021. doi: 10.3748/wjg.v27.i20.2586
Figure 4 Effects of long noncoding RNA W42 expression on tumor growth in hepatocellular carcinoma nude mouse model.
A: SMMC7721 cells (5 × 106) stably expressing long noncoding RNA (lncRNA) W42 were inoculated into hepatocellular carcinoma (HCC) nude mice, and the effect of lncRNA W42 on HCC tumor growth was examined every 3 d for 36 d (n = 8). Thirty-six days after injection, tumors were dissected from the mice in the lncRNA W42 knockdown and control groups. Representative images are shown; B: The growth rate of tumors in the lncRNA W42 knockdown group was lower than that in the control group. mean ± SE for eight mice in each group. cP < 0.001 compared with the control group; C: The weights of tumors dissected from mice in the lncRNA W42 knockdown group were significantly lower than those of their control counterparts. The results are shown as the mean ± SE for eight mice in each group. bP < 0.01 compared with control cells by two-sided t test. LncRNA: Long noncoding RNA.
- Citation: Lei GL, Niu Y, Cheng SJ, Li YY, Bai ZF, Yu LX, Hong ZX, Liu H, Liu HH, Yan J, Gao Y, Zhang SG, Chen Z, Li RS, Yang PH. Upregulation of long noncoding RNA W42 promotes tumor development by binding with DBN1 in hepatocellular carcinoma. World J Gastroenterol 2021; 27(20): 2586-2602
- URL: https://www.wjgnet.com/1007-9327/full/v27/i20/2586.htm
- DOI: https://dx.doi.org/10.3748/wjg.v27.i20.2586