Copyright
©The Author(s) 2021.
World J Gastroenterol. May 28, 2021; 27(20): 2474-2494
Published online May 28, 2021. doi: 10.3748/wjg.v27.i20.2474
Published online May 28, 2021. doi: 10.3748/wjg.v27.i20.2474
Drug regimen | Age range in yr | Sample size | Genotype(s) | Number of patients with SVR12, % | Ref. |
Sofosbuvir/ledipasvir | 12-17 | 100 | 1 | 98/100 (98) | Balistreri et al[25] |
6-11 | 92 | 1, 3, 4 | 91/92 (99) | Murray et al[26] | |
3-5 | 34 | 1, 4 | 33/34 (97) | Schwarz et al[27] | |
Sofosbuvir plus ribavirin | 12-17 | 52 | 2, 3 | 51/52 (98) | Wirth et al[33] |
6-11 | 41 | 41/41 (100) | Rosenthal et al[34] | ||
3-5 | 13 | 12/13 (92) | Rosenthal et al[34] | ||
Sofosbuvir/velpatasvir | 12-17 | 102 | 1, 2, 3, 4 | 97/102 (95) | Sokal et al[35] |
6-11 | 73 | 68/73 (93) | Sokal et al[35] | ||
3-5 | 41 | 34/41 (83) | Sokal et al[35] | ||
Glecaprevir/pibrentasvir | 12-17 | 47 | 1, 2, 3, 4 | 47/47 (100) | Jonas et al[36] |
6-11 | 32 | 31/32 (97) | Jonas et al[37] | ||
3-5 | 16 | 15/16 (96) | Jonas et al[37] | ||
Ombitasvir/paritaprevir/ritonavir ± dasabuvir ± ribavirin | 12-17 | 38 | 1, 4 | 38/38 (100) | Leung et al[134] |
6-11 | 26 | 1 | 25/26 (95) | Rosenthal et al[135] | |
Elbasvir/grazoprevir | 12-17 | 22 | 1, 4 | 22/22 (100) | Wirth et al[136] |
6-11 | 17 | 17/17 (100) | Wirth et al[136] | ||
3-5 | 18 | 18/18 (100) | Wirth et al[136] | ||
Sofosbuvir/velpatasvir/voxilaprevir | 12-17 | 21 | 1, 2, 3, 4 | 21/21 (100) | Bansal et al[137] |
Sofosbuvir plus daclatasvir | 15-17 | 13 | 4 | 13/13 (100) | El-Sayed et al[138] |
13-17 | 10 | 10/10 (100) | El-Shabrawi et al[139] | ||
12-17 | 30 | 29/29 (100) | Yakoot et al[140] | ||
8-17 | 40 | 1, 4 | 39/39 (100) | Abdel Ghaffar et al[141] | |
7-13 | 14 | 3 | 14/14 (100) | Padhi et al[57] |
- Citation: Nicastro E, Norsa L, Di Giorgio A, Indolfi G, D'Antiga L. Breakthroughs and challenges in the management of pediatric viral hepatitis. World J Gastroenterol 2021; 27(20): 2474-2494
- URL: https://www.wjgnet.com/1007-9327/full/v27/i20/2474.htm
- DOI: https://dx.doi.org/10.3748/wjg.v27.i20.2474