Copyright
©The Author(s) 2021.
World J Gastroenterol. May 14, 2021; 27(18): 2160-2176
Published online May 14, 2021. doi: 10.3748/wjg.v27.i18.2160
Published online May 14, 2021. doi: 10.3748/wjg.v27.i18.2160
Figure 4 Effects of partially hydrolyzed guar gum on toll-like receptor signaling through the gut-liver axis.
A: Toll-like receptor (TLR) 4 mRNA expression; B: TLR9 mRNA expression in the liver. mRNA expression was evaluated using real-time polymerase chain reaction; C: Endotoxin levels in the portal vein. Endotoxin levels were measured using the chromogenic Limulus Amebocyte Lysate Endotoxin Assay kit. Data represent the mean ± SD of seven mice. aP < 0.05 significant differences compared to the control group; bP < 0.05 significant differences between the 2 selected groups. NAFLD: Non-alcoholic fatty liver disease; PHGG: Partially hydrolyzed guar gum; TLR: Toll-like receptor.
- Citation: Takayama S, Katada K, Takagi T, Iida T, Ueda T, Mizushima K, Higashimura Y, Morita M, Okayama T, Kamada K, Uchiyama K, Handa O, Ishikawa T, Yasukawa Z, Okubo T, Itoh Y, Naito Y. Partially hydrolyzed guar gum attenuates non-alcoholic fatty liver disease in mice through the gut-liver axis. World J Gastroenterol 2021; 27(18): 2160-2176
- URL: https://www.wjgnet.com/1007-9327/full/v27/i18/2160.htm
- DOI: https://dx.doi.org/10.3748/wjg.v27.i18.2160