Copyright
©The Author(s) 2021.
World J Gastroenterol. May 14, 2021; 27(18): 2160-2176
Published online May 14, 2021. doi: 10.3748/wjg.v27.i18.2160
Published online May 14, 2021. doi: 10.3748/wjg.v27.i18.2160
Figure 2 Effects of partially hydrolyzed guar gum on hepatic inflammation and fibrosis in the non-alcoholic fatty liver disease model.
A: Tumor necrosis factor-α; B: Monocyte chemotactic protein-1; C: Collagen 1a1; D: α smooth muscle actin mRNA expression in the liver. mRNA expression was evaluated using real-time polymerase chain reaction. Data represent the mean ± SD of seven mice. aP < 0.05 significant differences compared to the control group; bP < 0.05 significant differences between the 2 selected groups. NAFLD: Non-alcoholic fatty liver disease; PHGG: Partially hydrolyzed guar gum; TNF-α: Tumor necrosis factor-α; MCP-1: Monocyte chemotactic protein-1; αSMA: α smooth muscle actin.
- Citation: Takayama S, Katada K, Takagi T, Iida T, Ueda T, Mizushima K, Higashimura Y, Morita M, Okayama T, Kamada K, Uchiyama K, Handa O, Ishikawa T, Yasukawa Z, Okubo T, Itoh Y, Naito Y. Partially hydrolyzed guar gum attenuates non-alcoholic fatty liver disease in mice through the gut-liver axis. World J Gastroenterol 2021; 27(18): 2160-2176
- URL: https://www.wjgnet.com/1007-9327/full/v27/i18/2160.htm
- DOI: https://dx.doi.org/10.3748/wjg.v27.i18.2160