Standard vs magnifying narrow-band imaging endoscopy for diagnosis of Helicobacter pylori infection and gastric precancerous conditions

Table 3 Diagnostic performance of standard and magnifying narrow-band imaging endoscopy for Helicobacter pylori gastritis, gastric atrophy, and intestinal metaplasia

Endoscopy	Diagnosis	Sensitivity (%)	Specificity (%)	PPV (%)	NPV (%)	Accuracy (%)	AUC
Standard	H. pylori gastritis	92.0a	95.6	97.4	87.0	93.3	0.93
	Moderate to severe atrophy	96.6	59.8	54.4	97.2	72.0	0.78
	Intestinal metaplasia, corpus	97.4	51.8	35.9	98.6	61.7	0.74
M-NBI	H. pylori gastritis	96.3a	95.6	97.5	93.5	96.1	0.96
	Moderate to severe atrophy	100	59.0	54.7	100	72.6	0.79
	Intestinal metaplasia, corpus	100	50.4	35.8	100	61.1	0.75

^aP = 0.016, McNemar test indicated a significant difference in sensitivity for diagnosis of Helicobacter pylori infection between standard and magnifying narrow-band imaging endoscopy. M-NBI: Magnifying narrow-band imaging; PPV: Positive predictive value; NPV: Negative predictive value; AUC: area under the curve; H. pylori: Helicobacter pylori.