Totally laparoscopic total gastrectomy using the modified overlap method and conventional open total gastrectomy: A comparative study

Table 5 Univariate analysis of risk factors for overall early, Clavien-Dindo classification ≥ 3, and esophagojejunostomy-related complications

Variables	Early complications		CDC ≥ 3 complications		EJ-related complications
	OR (95%CI)	P value	OR (95%CI)	P value	OR (95%CI)	P value
Type of surgery		0.518		0.428		0.090
TLTG	1		1		1
OTG	1.202 (0.688-2.100)		1.373 (0.628-3.002)		3.209 (0.833–12.356)
Age		0.289		0.051		0.035
< 60	1		1		1
≥ 60	1.358 (0.772-2.390)		2.347 (0.997-5.525)		9.220 (1.164-73.022)
BMI		0.045		0.380		0.402
< 25	1		1		1
≥ 25	1.773 (1.012-3.109)		1.419 (0.649-3.101)		1.678 (0.500-5.633)
ASA score		0.030		0.036
1-2	1		1
3	3.224 (1.122-9.265)		3.682 (1.088-12.456)
Number of comorbidities		0.342				0.752
0-2	1				1
> 2	1.631 (0.594-4.480)				1.406 (0.170-11.599)
Combined operation		0.685		0.381		0.735
No	1		1		1
Yes	0.833 (0.346-2.008)		0.515 (0.117-2.272)		0.697 (0.086-5.618)
History of abdominal surgery		0.130		0.323
No	1		1		1
Yes	1.640 (0.864-3.111)		1.554 (0.648-3.726)		1.408 (0.362-5.478)	0.622
Tumor size		0.521		0.442		0.053
< 5 cm	1		1		1
≥ 5 cm	0.830 (0.470-1.466)	0.521	0.727 (0.323-1.638)		3.786 (0.983-14.585)
Operation time		0.225		0.605		0.805
< 150 min	1		1		1
≥ 150 min	1.414 (0.808-2.477)		1.230 (0.562-2.692)		1.165 (0.347-3.912)
Retrieved lymph node		0.714		0.662		0.246
< 30	1		1		1
≥ 30	0.888 (0.471-1.676)		1.235 (0.480-3.181)		3.416 (0.429-27.170)
Pathologic tumor stage		0.418		0.864		0.875
I	1		1		1
II	0.666 (0.328-1.351)		1.246 (0.497-3.126)		0.701 (0.138-3.568)
III	0.704 (0.346-1.431)		0.950 (0.348-2.592)		1.119 (0.27-4.617)

Values are expressed as mean ± SD or n (%). TLTG: Totally laparoscopic total gastrectomy; OTG: Open total gastrectomy; CDC: Clavien-Dindo classification; EJ: Esophagojejunostomy; CI: Confidence interval; OR: Odds ratio.