S100 calcium binding protein A6 and associated long noncoding ribonucleic acids as biomarkers in the diagnosis and staging of primary biliary cholangitis

Table 2 Top 10 dysregulated genes in bile duct ligation and sham mice

Gene name	Transcript	Lg fold change
Up-regulated
Hmgb2	ENSMUSG00000054717	3.53
Rc3h2	ENSMUSG00000075376	3.33
Adamts1	ENSMUSG00000022893	3.15
Serpine1	ENSMUSG00000037411	3.08
S100a6	ENSMUSG00000001025	2.98
Pald1	ENSMUSG00000020092	2.67
Gsta4	ENSMUSG00000032348	2.50
D17H6S56E-5	NM_033075	2.46
Acta2	ENSMUSG00000035783	2.39
Ifi204	ENSMUSG00000073489	2.33
Down-regulated
Mcm10	ENSMUSG00000026669	3.23
Upp2	ENSMUSG00000026839	2.85
2810043O03Rik	AK012901.1	2.59
Dnaaf5	ENSMUSG00000025857	2.41
Sva	ENSMUSG00000023289	2.40
Naca	ENSMUSG00000061315	2.35
Dhps	ENSMUSG00000060038	2.33
Cdh15	ENSMUSG00000031962	2.26
Gzmm	ENSMUSG00000054206	2.20
Alox12	ENSMUSG00000000320	2.15

2810043O03Rik: RIKEN complementary deoxyribonucleic acid 2810043O03 gene; Acta2: Actin alpha 2, smooth muscle; Adamts1: A disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1; Alox12: Arachidonate 12-lipoxygenase; Cdh15: Cadherin 15; D17H6S56E-5: Deoxyribonucleic acid segment, Chr 17, human D6S56E 5; Dhps: Deoxyhypusine synthase; Dnaaf5: Dynein, axonemal assembly factor 5; Gsta4: Glutathione S-transferase alpha 4; Gzmm: Granzyme M (lymphocyte met-ase 1); Hmgb2: High mobility group box 2; Ifi204: Interferon activated gene 204; Mcm10: Minichromosome maintenance 10 replication initiation factor; Naca: Nascent polypeptide-associated complex alpha polypeptide; Pald1: Phosphatase domain containing paladin 1; Rc3h2: Ring finger and CCCH-type domains 2; S100A6: S100 calcium binding protein A6; Serpine1: Serpin family E member 1; Sva: Seminal vesicle antigen; Upp2: Uridine phosphorylase 2.