BRCA mutated pancreatic cancer: A change is coming

Table 1 Summary of studies of incidence of germline BRCA mutations in unselected pancreatic cancer cohorts

Ref.	Year	Population	Cohort size (Number AJ)	Germline BRCA1 pathogenic mutation incidence (%)	Germline BRCA2 pathogenic mutation incidence (%)	Combined germline BRCA mutation Incidence
Holter et al[23]	2015	North American	306 (33)	1.0%	3.6%	4.6%
Brand et al[24]	2018	North American	298 (26)	1.3%	1.3%	2.6%
Mizukami et al[25]	2020	Japanese	1005 (-)	1.7%	2.5%	4.2%
Grant et al[6]	2015	North American	290 (13)	0.3%	0.7%	1%
Lowery et al[26]	2018	North American	615 (111)	2.3%	5.7%	8%

AJ: Ashkenazi Jewish; BRCA: Breast cancer susceptibility gene.