Resection of pancreatic cystic neoplasms in recurrent acute pancreatitis prevents recurrent pancreatitis but does not identify more malignancies

Table 4 Characteristics of patients with intra-ductal papillary mucinous neoplasm with and without recurrent acute pancreatitis

	With RAP (n = 23)	Without RAP (n = 78)	Risk difference [95%CI]	P value
	n (%)	n (%)
Median age	64 (IQR 17)	67 (IQR 12)	NA	0.64
Sex (M)	13 (56.5)	38 (48.7)	NA	0.51
Location of cyst
Head	16 (69.6)	46 (59)	0.11 [-0.11, 0.32]	0.34
Body/Tail	7 (30.4)	32 (41)	-0.11 [-0.32, 0.11]	0.34
Main pancreas duct > 10	4 (17.4)	10 (12.8)	0.05 [-0.13, 0.22]	0.60
Cyst size > 3 cm	6 (26)	36 (46.2)	-0.20 [-0.41, 0.01]	0.06
Solid component	5 (21.7)	20 (25.6)	-0.04 [-0.23, 0.16]	0.69
Malignancy	6 (26.1)	23 (29.5)	-0.03 [-0.24, 0.17]	0.75
Pathological subtype
Intestinal	8 (34.8)	10 (12.8)	0.22 [0.01, 0.43]	0.04
Gastric	3 (13)	42 (53.9)	-0.41 [-0.58, -0.23]	< 0.0001
Pancreatobiliary	7 (30.4)	15 (19.2)	0.11 [-0.10, 0.32]	0.29
Oncocytic	0 (0%)	3 (3.8)	-0.04 [-0.11, 0.03]	0.30
Unknown	5 (21.8)	8 (10.3)	0.11 [-0.07, 0.30]	0.22

RAP: Recurrent acute pancreatitis; IQR: Interquartile range; CI: Confidence interval.