Resection of pancreatic cystic neoplasms in recurrent acute pancreatitis prevents recurrent pancreatitis but does not identify more malignancies

Table 3 Characteristics of all patients (n = 172)

	With RAP (n = 29)	Without RAP (n = 143)	Risk difference [95%CI]	P value
	n (%)	n (%)
Median age	61 (IQR 18)	65 (IQR 15)	NA	0.65
Sex (M)	13 (44.8)	58 (40.6)	NA	0.67
Location of cyst
Head	16 (55.2)	65 (45.5)	0.10 [-0.10, 0.30]	0.34
Neck	2 (6.9)	7 (4.9)	0.02 [-0.08, 0.12]	0.69
Body	8 (27.6)	32 (22.4)	0.05 [-0.12, 0.23]	0.56
Tail	3 (10.3)	37 (25.9)	-0.16 [-0.29, -0.02]	0.02
Diffuse	0 (0)	2 (1.4)	-0.01 [-0.06, 0.04]	0.59
Main pancreas duct > 10	4 (13.8)	10 (7.0)	0.07 [-0.06, 0.20]	0.31
Cyst size > 3	6 (20.7)	36 (25.2)	-0.04 [-0.21, 0.12]	0.59
Solid component	7 (24.1)	46 (32.2)	-0.08 [-0.25, 0.09]	0.36
Malignancy	6 (20.7)	24 (16.8)	0.04 [-0.12, 0.20]	0.63
Pathological subtype
Intestinal	10 (34.5)	11 (7.7)	0.27 [0.09, 0.45]	0.003
Gastric	3 (10.3)	43 (30.1)	-0.20 [-0.33, -0.06]	0.004
Pancreatobiliary	7 (24.1)	15 (10.5)	0.14 [-0.03, 0.30]	0.10
Oncocytic	0 (0)	3 (2.1)	-0.02 [-0.07, 0.03]	0.43
Unknown	9 (31.0)	71 (49.7)	-0.19 [-0.37, 0.001]	0.05
Cyst type
IPMN total	23 (79.3)	78 (54.5)	0.25 [0.08, 0.41]	0.004
BD-IPMN	15 (51.7)	44 (30.8)	0.21 [0.01, 0.41]	0.04
MD-IPMN	8 (27.6)	34 (23.8)	0.04 [-0.14, 0.22]	0.67
Non-IPMN	6 (20.7)	65 (45.5)	-0.25 [-0.42, -0.08]	0.004

RAP: Recurrent acute pancreatitis; IPMN: Intra-ductal papillary mucinous neoplasm; MD-IPMN: Main duct-IPMN; BD-IPMN: Branch duct-IPMN; IQR: Interquartile range; CI: Confidence interval.