Retrospective Study
Copyright ©The Author(s) 2021.
World J Gastroenterol. Mar 28, 2021; 27(12): 1194-1212
Published online Mar 28, 2021. doi: 10.3748/wjg.v27.i12.1194
Table 3 Previous studies examining the efficacy of cytapheresis in refractory ulcerative colitis
Ref.
Refractory type
Number of patients
Evaluation items1
Rate of remission (evaluation time)
Rate of steroid- free remission (evaluation time)
Naganuma et al[44] (2004)SR10InductionSevere 20%, moderate 70%
Giampaolo et al[45] (2006)SR8Induction, sustained remission100%100%, 12.5% (12 mo)
Ricart et al[46] (2007)SD20Induction, sustained remission42.1% (17 wk)36.8% (17 wk), 85.7% (12 mo)
Cabriada et al[47] (2010)SD18Induction, sustained remission55% (1 mo), 75% (12 mo)
Cabriada et al[48] (2012)SD142Induction, sustained remission37% (1 mo), 51%2 (12 mo)
Sacco et al[49] (2013)SD + SR83 (SD 55, SR 28)Induction, sustained remission71%, 48% (12 mo)
Yokoyama et al[43] (2014)SD + SR401 (SD 229, SR 172)InductionSD: 64.6% (2 wk), SR: 70.9 (2 wk)
Dignass et al[50] (2016)SD86Induction39.3% (12 wk)22.6% (12 wk)
Imperiali et al[51] (2017)SD33Induction36% (12 mo)
Dignass et al[52] (2018)SD95Induction34.0% (24 wk), 33.0% (48 wk)19.2% (24 wk), 19.2% (48 wk)
Domènech et al[53] (2018)SD63Induction13% (24 wk)
Present studySD + SR55 (SD 33, SR 21)Induction, sustained remissionSD: 69.7% (4 wk), SR: 66.7% (4 wk)SD: 42.4% (4 wk) SR: 47.6% (4 wk); SD: 69.2% (12 mo), SR: 63.6% (12mo)