Perioperative blood transfusion decreases long-term survival in pediatric living donor liver transplantation

Table 1 Modified Clavien-Dindo classification for pediatric liver transplantation

Grade	Definition
I	Complication that requires the use of simple analgesics, antipyretics, anti-emetics, diuretics, electrolytes and physiotherapy
II	Complication requiring other drugs, different from grade I, blood transfusion or parenteral nutrition
III	Complication requiring surgical, endoscopic or radiologic intervention under any kind of anesthesia
IIIa	Low complexity procedures: Small and medium surgery, endoscopy and colonoscopy, US, CT, ERCP or PTCD, arteriography and angioplasty of portal vein or suprahepatic veins and hepatic artery, biopsies, simple teeth extractions, drainages, ostomies and central catheter passage for medication, dialysis or chemotherapy
IIIb	High complexity procedures: Large surgery, multiple teeth extractions, vascular and biliodigestive re-anastomosis, laparotomy and thoracotomy
IV	Life-threatening complication (including CNS1 complications) requiring ICU admission
IVa	Dysfunction of one organ (including dialysis)
IVb	Dysfunction of two or more organs
V	Death of patient

¹Cerebral hemorrhage, ischemic stroke, subarachnoid bleeding, excluding transient ischemic attack. Suffix “d” (for "disability") indicates that the patient still has complication, at time of discharge, requiring follow-up and must be entered to the degree of complication (e.g., IVa-d degree). US: Ultrasound; CT: Computed tomography; ERCP: Endoscopic retrograde cholangiopancreatography; PTCD: Percutaneous transhepatic cholangiography or drainage; CNS: Central nervous system; ICU: Intensive care unit.