Huanglian decoction suppresses the growth of hepatocellular carcinoma cells by reducing CCNB1 expression

Figure 6 Huanglian decoction suppressed hepatocellular carcinoma cell growth in vitro. A: Time- and dose-dependent effects of Huanglian decoction treatment on the viability of both PLC/PRF/5 and HepG2 cells; B: Huanglian decoction can induce apoptosis of both PLC/PRF/5 and HepG2 cells; C: Huanglian decoction can reduce the migration activity of both PLC/PRF/5 and HepG2 cells; D: Huanglian decoction can reduce the invasion activity of both PLC/PRF/5 and HepG2 cells. ^aP < 0.05 vs negative control (NC) group; ^bP < 0.01 vs NC group; ^cP < 0.001 vs NC group. FITC: Fluorescein isothiocyanate.