Valuable clinical indicators for identifying infantile-onset inflammatory bowel disease patients with monogenic diseases

Table 6 Comparison of risk factors among infantile-onset inflammatory bowel disease patients with or without IL-10RA mutation and non-monogenic inflammatory bowel disease (median, interquartile range)

	IL-10RA M-IBD	Non-IL-10RA M-IBD	NM-IBD	P value
Ferritin (ng/mL)	55.90 (53.12, 74.73)	45.25 (16.58, 68.70)	15.30 (14.55, 17.95)1	< 0.001
IL-10 (pg/mL)	85.20 (66.20, 125.00)1	8.90 (5.00, 85.20)	5.00 (5.00, 9.11)	< 0.001
Median onset age (mo)	0.04 (0.00, 0.08)1	2 (0.41, 4.08)	3.99 (3, 9)	< 0.001
Perianal disease (%)	32 (91.43)1	3 (33.33)	7 (24.14)	0.002

¹Compared with the other two groups, adjusted P value < 0.01. M-IBD: Monogenic inflammatory bowel disease; NM-IBD: Non-monogenic inflammatory bowel disease; IL: Interleukin.