Exosomal miR-182 regulates the effect of RECK on gallbladder cancer

Figure 4 Exosomal microRNA 182 can promote cell proliferation, migration and invasion, and inhibit apoptosis and expression of reversion-inducing-cysteine-rich protein with kazal motifs. A: Exosomal microRNA 182 (miR-182) enhanced the viability of gallbladder cancer (GC) cells; B: Exosomal miR-182 promoted cell invasion and migration; C: Effects of exosomal miR-182 on caspase 3, caspase 9, E-cadherin, B-cell lymphoma 2 (Bcl-2), Bcl-2-associated X protein, N-cadherin, and β-catenin in GC cells; D: Exosomal miR-182 inhibited apoptosis; E: Exosomal miR-182 inhibited reversion-inducing-cysteine-rich protein with kazal motifs expression. ^aP < 0.05, ^bP < 0.01, and ^cP < 0.001 vs the negative control (NC) group.