Role of alcohol in pathogenesis of hepatitis B virus infection

doi:10.3748/wjg.v26.i9.883

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Mar 7, 2020 (publication date) through Nov 4, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Mar 7, 2020; 26(9): 883-903
Published online Mar 7, 2020. doi: 10.3748/wjg.v26.i9.883

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Figure 2 Mechanisms of alcohol and hepatitis B virus-infection induced liver injury. Alcohol and hepatitis B virus together increase hepatitis B virus replication, oxidative stress, and cell organelle stress (endoplasmic reticulum and Golgi stress) which ultimately suppresses both adaptive and innate immune response, thereby leading to end- stage liver diseases. HBV: Hepatitis B virus; ER: Endoplasmic reticulum; IFN: Interferon; IL: Interleukin; MHC: Major histocompatibility complex; NK: Natural killers.

Citation: Ganesan M, Eikenberry A, Poluektova LY, Kharbanda KK, Osna NA. Role of alcohol in pathogenesis of hepatitis B virus infection. World J Gastroenterol 2020; 26(9): 883-903
URL: https://www.wjgnet.com/1007-9327/full/v26/i9/883.htm
DOI: https://dx.doi.org/10.3748/wjg.v26.i9.883