Diverting colostomy is an effective and reversible option for severe hemorrhagic radiation proctopathy

Table 5 Quality of life in the colostomy group and conservative group of chronic radiation proctopathy patients based on the EORTC QLQ-C30 scale

QLQ-C30 scale	Reference: Normal German population	Colostomy group, n = 14, mean ± SD				Conservative group, n = 25, mean ± SD
		Pretreat-ment	Follow-up	Δ(FU)-Pre2	Signifi-cance1	Pretreat-ment	Follow-up	Δ(FU)-Pre	Signifi-cance1
Global health	63.2	23.1 ± 15.1	63.1 ± 18.3	40	< 0.001	47.1 ± 21.5	62.3 ± 25.0	15.2	0.033
Physical function	82.6	50.7 ± 17.8	87.1 ± 13.7	36.4	< 0.001	78.0 ± 22.7	78.6 ± 26.1	0.6	0.856
Role function	75	34.3 ± 23.9	89.3 ± 20.5	55	< 0.001	77.5 ± 24.9	77.5 ± 29.1	0	0.775
Emotional function	62.2	46.3 ± 27.4	85.7 ± 14.9	39.4	< 0.001	75.7 ± 17.6	80.8 ± 23.8	5.1	0.384
Cognition function	81.3	92.6 ± 12.7	95.2 ± 9.8	2.6	1.0	94.2 ± 15.6	95.7 ± 9.0	1.5	0.798
Social function	78.4	43.5 ± 28.9	79.8 ± 18.0	36.3	< 0.001	91.3 ± 20.6	89.1 ± 21.1	-2.2	0.916
Fatigue	34.1	72.8 ± 12.9	10.3 ± 18.5	-62.5	< 0.001	26.6 ± 24.1	23.2 ± 27.2	-3.4	0.695
Nausea/ vomiting	5.7	4.6 ± 15.5	0 ± 0	-4.6	-	5.1 ± 15.4	6.5 ± 16.5	1.4	0.655
Pain	33.1	44.4 ± 28.3	9.5 ± 15.1	-34.9	< 0.001	14.5 ± 21.5	11.6 ± 18.4	-2.9	0.481
Dyspnea	18.8	42.6 ± 31.0	4.8 ± 11.7	-37.8	< 0.001	14.5 ± 19.7	8.7 ± 18.0	-5.8	0.210
Insomnia	38.5	48.1 ± 35.5	11.9 ± 20.3	-36.2	< 0.001	21.7 ± 21.6	26.1 ± 31.7	4.4	0.287
Appetite loss	9.4	22.2 ± 27.2	0 ± 0	-22.2	-	10.1 ± 25.5	8.7 ± 18.0	-1.4	0.785
Constipation	9.1	9.3 ± 14.9	9.5 ± 15.1	-0.2	1.0	8.7 ± 20.6	7.2 ± 22.4	-1.5	0.414
Diarrhea	9.2	33.3 ± 33.3	9.5 ± 26.5	-23.8	< 0.001	11.6 ± 23.8	2.9 ± 9.6	-8.7	0.078
Financial difficulties	17.1	59.3 ± 26.2	23.8 ± 31.9	-35.5	< 0.001	26.1 ± 31.7	24.6 ± 30.5	-1.5	0.595

¹Wilcoxon rank-sum test.

²Point (follow-up) – point (pretreatment). Δ(FU): Change in follow-up; SD: Standard deviation.