Promising key genes associated with tumor microenvironments and prognosis of hepatocellular carcinoma

doi:10.3748/wjg.v26.i8.789

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Feb 28, 2020 (publication date) through Nov 27, 2024

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World Journal of Gastroenterology

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1007-9327

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World J Gastroenterol. Feb 28, 2020; 26(8): 789-803
Published online Feb 28, 2020. doi: 10.3748/wjg.v26.i8.789

Table 1 Genes with significant prognostic value in hepatocellular carcinoma identified in both The Cancer Genome Atlas and Integrative Molecular Database of Hepatocellular Carcinoma

Times of gene verification by HCC cohorts from HCCDB	Down-regulated gene in low score group	Up-regulated gene in low score group
2	*MS4A1, KLRB1, ITK, GZMH, ADH1C, UGT2B15, GPR171, CD40LG, CD5, FBLN2, CCL21, ATP2A3, IL16, ELN*
1	*SELL, CD5L, KLRK1, CXCR6, TRAF3IP3, CD79A, FLT3, GZMA, SPN, PRKCQ, SIDT1, RERGL, INMT, C11orf21, ZAP70, FLI1, DOK5, ITM2A, PHLDA3, APLNR, CFHR3, NLRC3, GIMAP1, FBLN5, DARC, SLFN12L, RASGRP2, SELP, ACAP1, C7, HTR2B, TNXB, SAMD3, PDZD4*	*CTSL2, MFAP2, TMC5, BACE2*

Genes in bold have not been previously reported for their prognostic value in hepatocellular carcinoma patients. HCC: Hepatocellular carcinoma; HCCDB: Integrative molecular database of hepatocellular carcinoma.

Citation: Pan L, Fang J, Chen MY, Zhai ST, Zhang B, Jiang ZY, Juengpanich S, Wang YF, Cai XJ. Promising key genes associated with tumor microenvironments and prognosis of hepatocellular carcinoma. World J Gastroenterol 2020; 26(8): 789-803
URL: https://www.wjgnet.com/1007-9327/full/v26/i8/789.htm
DOI: https://dx.doi.org/10.3748/wjg.v26.i8.789