Copyright
©The Author(s) 2020.
World J Gastroenterol. Feb 28, 2020; 26(8): 777-788
Published online Feb 28, 2020. doi: 10.3748/wjg.v26.i8.777
Published online Feb 28, 2020. doi: 10.3748/wjg.v26.i8.777
Screening within 30 d before donation start date |
Exclusion criteria |
Fever of unknown origin |
Significant medical history other than resolved trauma or routine surgery |
Abnormal body mass index (normal = 18.5 to 25.0) |
Metabolic syndrome |
Previous or current malignant condition |
Atopic disease |
Chronic pain syndrome |
Irritable bowel syndrome |
Idiopathic chronic constipation |
Chronic diarrhea |
Long term use of laxatives |
Personal or family history of inflammatory bowel disease |
History of Clostridioides difficile infection |
Unexplained gastrointestinal illness |
Autoimmune diseases |
Neurological diseases |
Active communicable illnesses (human immunodeficiency virus, chronic hepatitis etc.) |
Travel to underdeveloped countries in past 12 mo |
Hospitalization within the past 12 mo |
Antibiotic exposure within the past 6 mo |
High risk sexual behavior (men having sex with men, multiple sexual partners) |
Health care worker |
Illicit drug use, recent tattoos or incarceration |
Immunosuppressive or antineoplastic medication use |
Recent ingestion of certain common allergens (e.g. Nuts, shellfish, peanuts, eggs etc.) |
Laboratory tests |
High-sensitivity C-reactive protein assay |
Lipid panel |
Comprehensive metabolic panel |
Complete blood count with differential |
Antinuclear antibodies |
Human chorionic gonadotrophin pregnancy test, if female |
Infectious disease screening tests |
Clostridioides difficile toxin gene polymerase chain reaction |
Bacterial enteric pathogen stool culture |
Rotavirus enzyme linked immunosorbent assay |
Helicobacter pylori antigen |
Vancomycin resistant enterococci rectal screen |
Carbepenem resistant enterobacteriaceae plating |
Nasal screen, plating |
Listeria monocytogenes plating |
Stool ova and parasites (including giardia, cryptosporidia and microsporidia) |
Screening within 14 d before donation start date |
Serology |
Human immunodeficiency virus (HIV-1 and HIV-2) p-24 antigen and antibody |
Syphilis enzyme immunoassay |
Hepatitis A antibody |
Hepatitis B surface antigen and surface antibody |
Hepatitis C antibody |
Plasma polymerase chain reaction assays for Epstein-Barr virus and Cytomegalovirus at first and last donations |
- Citation: Gupta A, Saha S, Khanna S. Therapies to modulate gut microbiota: Past, present and future. World J Gastroenterol 2020; 26(8): 777-788
- URL: https://www.wjgnet.com/1007-9327/full/v26/i8/777.htm
- DOI: https://dx.doi.org/10.3748/wjg.v26.i8.777