Review
Copyright ©The Author(s) 2020.
World J Gastroenterol. Feb 28, 2020; 26(8): 777-788
Published online Feb 28, 2020. doi: 10.3748/wjg.v26.i8.777
Table 1 Donor screening criteria[15,90]
Screening within 30 d before donation start date
Exclusion criteria
Fever of unknown origin
Significant medical history other than resolved trauma or routine surgery
Abnormal body mass index (normal = 18.5 to 25.0)
Metabolic syndrome
Previous or current malignant condition
Atopic disease
Chronic pain syndrome
Irritable bowel syndrome
Idiopathic chronic constipation
Chronic diarrhea
Long term use of laxatives
Personal or family history of inflammatory bowel disease
History of Clostridioides difficile infection
Unexplained gastrointestinal illness
Autoimmune diseases
Neurological diseases
Active communicable illnesses (human immunodeficiency virus, chronic hepatitis etc.)
Travel to underdeveloped countries in past 12 mo
Hospitalization within the past 12 mo
Antibiotic exposure within the past 6 mo
High risk sexual behavior (men having sex with men, multiple sexual partners)
Health care worker
Illicit drug use, recent tattoos or incarceration
Immunosuppressive or antineoplastic medication use
Recent ingestion of certain common allergens (e.g. Nuts, shellfish, peanuts, eggs etc.)
Laboratory tests
High-sensitivity C-reactive protein assay
Lipid panel
Comprehensive metabolic panel
Complete blood count with differential
Antinuclear antibodies
Human chorionic gonadotrophin pregnancy test, if female
Infectious disease screening tests
Clostridioides difficile toxin gene polymerase chain reaction
Bacterial enteric pathogen stool culture
Rotavirus enzyme linked immunosorbent assay
Helicobacter pylori antigen
Vancomycin resistant enterococci rectal screen
Carbepenem resistant enterobacteriaceae plating
Nasal screen, plating
Listeria monocytogenes plating
Stool ova and parasites (including giardia, cryptosporidia and microsporidia)
Screening within 14 d before donation start date
Serology
Human immunodeficiency virus (HIV-1 and HIV-2) p-24 antigen and antibody
Syphilis enzyme immunoassay
Hepatitis A antibody
Hepatitis B surface antigen and surface antibody
Hepatitis C antibody
Plasma polymerase chain reaction assays for Epstein-Barr virus and Cytomegalovirus at first and last donations