Role of Tenascin-X in regulating TGF-β/Smad signaling pathway in pathogenesis of slow transit constipation

Figure 1 Immunohistochemical staining for c-Kit and Tenascin-X proteins. A: High expression of c-Kit in the normal colon; B: Low expression of c-Kit in the slow transit constipation colon. The arrows indicate interstitial cells of Cajal showing brown-yellow c-Kit staining, suggesting that the number of interstitial cells of Cajal was reduced in the slow transit constipation group (200 ×).