Pre-hepatectomy type IV collagen 7S predicts post-hepatectomy liver failure and recovery

Table 6 Cox proportional hazards analysis to identify predictors of postoperative recovery of liver function to achieve serum albumin > 2.8 g/dL

Factors	Univariate analysis		Multivariate analysis
	OR (95%CI)	P value	OR (95%CI)	P value
Age, yr (mean)	0.985 (0.973-0.996)	0.008		0.18
Sex, male/female		0.059		0.457
Child-Pugh score	0.573 (0.424-0.776)	< 0.001		0.611
Cholinesterase (IU/L)	1.002 (1.001-1.003)	0.001		0.39
ICG-R15 (%)	0.979 (0.962-0.996)	0.008		0.983
Type IV collagen 7S (ng/mL)	0.841 (0.787-0.899)	< 0.001	0.759 (0.659-0.875)	< 0.001
Hyaluronic acid (ng/mL)	0.996 (0.994-0.999)	0.004		0.292
ARFITM (v/s)	0.723 (0.545-0.959)	0.024		0.774
CRP (mg/dL)	0.808 (0.685-0.953)	0.011		0.192
Extent of hepatic resection[26]	0.830 (0.722-0.955)	0.009		0.636

ICG-R15: Indocyanine green retention rate at 15 min; ARFI: Acoustic radiation force impulse; CRP: C-reactive protein.