Pre-hepatectomy type IV collagen 7S predicts post-hepatectomy liver failure and recovery

Table 5 Cox proportional hazards analysis to identify predictors of postoperative recovery of liver function to achieve serum total bilirubin < 2 mg/dL

Factors	Univariate analysis		Multivariate analysis
	OR (95%CI)	P value	OR (95%CI)	P value
Age, yr (mean)		0.275		0.53
Sex, male/female		0.127		0.222
Child-Pugh score	0.749 (0.565-0.994)	< 0.001		0.21
PT-INR (INR)	0.195 (0.47-0.803)	0.024		0.155
Cholinesterase (IU/L)	1.002 (1.001-1.004)	0.003		0.106
ICG-R15 (%)		0.165
Type IV collagen 7S (ng/mL)	0.905 (0.851-0.926)	0.001	0.906 (0.851-0.962)	0.001
Hyaluronic acid (ng/mL)		0.552
ARFITM (v/s)		0.056
CRP (mg/dL)		0.118
Extent of hepatic resection[26]		0.159

PT-INR: Prothrombin time-international normalized ratio; ICG-R15: Indocyanine green retention rate at 15 min; ARFI: Acoustic radiation force impulse; CRP: C-reactive protein.