Pre-hepatectomy type IV collagen 7S predicts post-hepatectomy liver failure and recovery

Table 4 Cox proportional hazards analysis to identify predictors of postoperative recovery of liver function to achieve Child-Pugh class A

Factors	Univariate analysis		Multivariate analysis
	OR (95%CI)	P value	OR (95%CI)	P value
Age, yr (mean)	0.984 (0.972-0.996)	0.007		0.837
Sex, male/female		0.688		0.656
Child-Pugh score	0.577 (0.427-0.780)	< 0.001		0.123
Cholinesterase (IU/L)	1.002 (1.001-1.003)	0.001		0.346
Total cholesterol (mg/dL)	1.004 (1.001-1.007)	0.024		0.932
ICG-R15 (%)	0.980 (0.964-0.997)	0.024		0.756
Type IV collagen 7S (ng/mL)	0.837 (0.784-0.894)	< 0.001	0.779 (0.682-0.890)	< 0.001
Hyaluronic acid (ng/mL)	0.996 (0.994-0.999)	0.003		0.179
ARFITM (v/s)	0.651 (0.490-0.866)	0.003		0.625
CRP (mg/dL)	0.792 (0.669-0.936)	0.006		0.142
Extent of hepatic resection[26]	0.813 (0.707-0.936)	0.004		0.64

ICG-R15: Indocyanine green retention rate at 15 min; ARFI: Acoustic radiation force impulse; CRP: C-reactive protein.