Pre-hepatectomy type IV collagen 7S predicts post-hepatectomy liver failure and recovery

Table 10 Preoperative liver function parameters in post-hepatectomy liver failure and non-post-hepatectomy liver failure patients in univariate and multivariate analyses for 91 patients

Factors	Univariate analysis		Multivariate analysis
	OR (95%CI)	P value	OR (95%CI)	P value
Age, yr (mean)		0.083		0.065
Sex, male/female		0.462		0.557
Child-Pugh score		0.347
Platelets (× 104/μL)		0.509
PT-INR (INR)		0.064
Aspartate aminotransferase (IU/L)		0.087
Alanine aminotransferase (IU/L)		0.468
Cholinesterase (IU/L)	0.986 (0.977-0.995)	0.003		0.348
Total cholesterol (mg/dL)		0.128
ICG-R15 (%)		0.643
Type IV collagen 7S (ng/mL)	1.514 (0.784-0.894)	< 0.001	2.178 (0.684-0.890)	0.005
Hyaluronic acid (ng/mL)	1.005 (1.001-1.009)	0.018		0.674
ARFITM (v/s)		0.145
CRP (mg/dL)		0.495
METAVIR score		0.801
Extent of hepatic resection[26]	2.296 (0.707-0.936)	0.009		0.86

PT-INR: Prothrombin time-international normalized ratio; ICG-R15: Indocyanine green retention rate at 15 min; ARFI: Acoustic radiation force impulse; CRP: C-reactive protein.