Liver stiffness and perfusion changes for hepatic sinusoidal obstruction syndrome in rabbit model

Table 1 Comparison of laboratory results between control and sinusoidal obstruction syndrome groups

Results	Days	Control group	SOS group	Differences	P value
AST (IU/L)	0	32.67 (-55.57, 120.9)	20.5 (-41.89, 82.89)	12.17 (-95.9, 120.23)	0.818
	3	24.67 (-63.57, 112.9)	23 (-39.39, 85.39)	1.67 (-106.4, 109.73)	0.975
	10	20.67 (-67.57, 108.9)	26.4 (-42.5, 95.3)	-5.73 (-117.68, 106.22)	0.917
	20	26.33 (-61.9, 114.57)	221.34 (130.35, 312.33)	-195.01 (-321.75, -68.26)	0.004b
ALT (IU/L)	0	38 (3.97, 72.03)	33.17 (9.11, 57.23)	4.83 (-36.84, 46.51)	0.813
	3	44.67 (10.64, 78.69)	41.83 (17.77, 65.89)	2.83 (-38.84, 44.51)	0.890
	10	33.67 (-0.36, 67.69)	25.41 (-1.18, 51.99)	8.26 (-34.92, 51.44)	0.697
	20	40.67 (6.64, 74.69)	109.35 (74.12, 144.58)	-68.69 (-117.67, -19.71)	0.008b
Tbil (mg/dL)	0	0.27 (-0.18, 0.72)	0.42 (0.1, 0.73)	-0.15 (-0.7, 0.4)	0.579
	3	0.63 (0.18, 1.08)	0.52 (0.2, 0.83)	0.12 (-0.43, 0.67)	0.666
	10	0.9 (0.45, 1.35)	1.18 (0.82, 1.53)	-0.28 (-0.85, 0.29)	0.328
	20	0.53 (0.08, 0.98)	0.96 (0.49, 1.43)	-0.43 (-1.07, 0.22)	0.186
Dbil (mg/dL)	0	0.1 (-0.08, 0.28)	0.12 (-0.01, 0.25)	-0.02 (-0.24, 0.21)	0.879
	3	0.13 (-0.05, 0.32)	0.17 (0.04, 0.3)	-0.03 (-0.26, 0.19)	0.760
	10	0.17 (-0.02, 0.35)	0.26 (0.12, 0.4)	-0.09 (-0.32, 0.14)	0.411
	20	0.13 (-0.05, 0.32)	0.47 (0.28, 0.65)	-0.33 (-0.59, -0.08)	0.013a

Values are estimated mean and 95% confidence interval.

^aP < 0.05.

^bP < 0.01. SOS: Sinusoidal obstruction syndrome; AST: Serum aspartate aminotransferase; ALT: Alanine aminotransferase; Tbil: Total bilirubin; Dbil: Direct bilirubin.