MiR-19a-3p regulates the Forkhead box F2-mediated Wnt/β-catenin signaling pathway and affects the biological functions of colorectal cancer cells

Figure 1 Expression of serum miR-19a-3p and Forkhead box F2 in colorectal cancer patients and their clinical value. A: The study group showed significantly higher miR-19a-3p expression than the control group, and miR-19a-3p was highly expressed in serum of colorectal cancer (CRC) patients. ^bP < 0.001; B: The study group showed significantly lower expression of Forkhead box F2 (FOXF2) than the control group, and FOXF2 had low expression in the CRC patients. ^bP < 0.001; C: The area under the curve of miR-19a-3p was 0.883; D: The area under the curve of FOXF2 was 0.850; E: The expression of serum miR-19a-3p was negatively related to that of FOXF2 in CRC patients (r = -0.836, ^bP < 0.001). CRC: Colorectal cancer; FOXF2: Forkhead box F2.