Expression of miR-1304 in patients with esophageal carcinoma and risk factors for recurrence

Table 9 Gene ontology enrichment analysis

ID	Term	Gene	Count	P value
GO: 0043392	Negative regulation of DNA binding	WFIKKN2, SP100, HAND2, HMOX1, HMGA2	5	0.001
GO: 0051091	Positive regulation of sequence-specific DNA binding transcription factor activity	IL6, SP100, HIPK2, PYCARD, HMGA2, TRIM22, TCF3, ATF2	8	0.001
GO: 0000122	Negative regulation of transcription from RNA polymerase II promoter	ATF7IP, SATB1, BACH2, SP100, GABPA, DICER1, YBX3, KLF16, ZEB2, HMGA2, ZNF345, ATF2, SUV39H2, VDR, OLIG3, MLX, PRMT6, HIPK2, ZNF431, TCF3, SMARCA2, SUDS3	22	0.002
GO: 0006351	Transcription, DNA-templated	XRCC5, ZNF555, IRX5, CCNT1, YBX3, BBX, TTLL5, ZNF250, ZEB2, ZNF652, ZNF184, VDR, OLIG3, PRMT6, ZNF426, KDM3B, BAZ2A, TCF3, MAP2K6, ATF7IP, SATB1, SP100, ZNF620, ZNF92, KLF16, SCAI, TRIM22, ATMIN, ZNF585B, FAM208A, SUV39H2, ZBTB25, EYA4, ZNF439, MLX, PARP14, HIPK2, ZNF431, ZNF432, SMARCA2, FOXD4L6, SUDS3, ZNF573, ZBTB8A	44	0.002
GO: 0006355	Regulation of transcription, DNA-templated	ZNF555, IRX5, YBX3, BBX, ZNF250, ZNF652, ATF2, VDR, ZNF184, ZNF426, KDM3B, BAZ2A, INSR, TCF3, MAP2K6, SATB1, ZNF620, ZNF92, SCAI, AFF1, HMGA2, TRIM22, ZNF585B, FAM208A, ZBTB25, EYA4, TULP4, ZNF439, PARP14, CDKN2AIP, MLX, ZNF431, ZNF432, SMARCA2, ZBTB8A, ZNF573	36	0.003
GO: 0005138	Interleukin-6 receptor binding	IL6, PYCARD, ADAM17	3	0.004
GO: 0015031	Protein transport	SLC7A6OS, RAB9A, RAB3D, KIF17, DUOXA1, RAB39A, VPS52, PKDCC, HOOK3, GOPC, SNX30, SNX20, EXOC6B	13	0.011
GO: 0050892	Intestinal absorption	F11R, VDR, KCNQ1	3	0.016
GO: 0042147	Retrograde transport, endosome to Golgi	SPAG9, RAB9A, STX16, VPS52, VPS26A	5	0.017
GO: 0032259	Methylation	METTL8, TRMT10B, SETD9, CARNMT1, NNMT	5	0.020
GO: 0032290	Peripheral nervous system myelin formation	NCMAP, DICER1	2	0.028
GO: 0005509	Calcium ion binding	PCDH11Y, PCDH11X, RPH3AL, DAG1, STIM1, MMP17, FSTL4, TTN, IQGAP1, CALU, ITPR2, PLSCR1, CALML4, TPT1, SYTL2, EGF, CALM2, CACNA1B	18	0.029
GO: 0008544	Epidermis development	SATB1, STS, ELF3, INSR, SCEL	5	0.033
GO: 0003677	DNA binding	XRCC5, ZNF555, AGFG1, KIAA1958, CCNT1, YBX3, BBX, ZNF250, ZEB2, ZNF345, ZNF652, ZNF184, VDR, OLIG3, HIST1H4C, ZNF426, BAZ2A, TCF3, SATB1, SP100, ZNF620, CHTF8, GABPA, HMGA2, ZBTB25, PLSCR1, ZNF439, RFC2, MLX, HIPK2, RAD18, ZNF432, ZNF573, ZBTB8A	34	0.035
GO: 0046872	Metal ion binding	ZNF555, MGAT5B, AGFG1, DICER1, ZNF250, ZEB2, ZNF345, ZNF652, ATF2, ZFC3H1, ZNF184, CLEC17A, FGG, HMOX1, ZC3H12B, ZNF426, KDM3B, STS, KCND3, NRXN3, ZNF620, ZNF92, KLF16, RPH3AL, ATMIN, ZNF585B, ZBTB25, EYA4, ZNF439, GNAQ, ADAM17, ZNF431, YME1L1, ZNF432, ADAM12, ZNHIT6, CACNA1D, UGP2, ZBTB8A, ZNF573	40	0.042
GO: 0070644	Vitamin D response element binding	VDR, TCF3	2	0.042
GO: 0005794	Golgi apparatus	STS, RAB39A, FGFRL1, VPS52, PKDCC, PRKG1, SART1, CALU, HOOK3, PLSCR1, NRAS, COPB1, STX16, GOPC, CNTNAP2, CAND1, B4GALT7, TRAPPC3, SLC30A7	19	0.044
GO: 0007173	Epidermal growth factor receptor signaling pathway	NRAS, ADAM17, EGF, IQGAP1	4	0.045