Expression of miR-1304 in patients with esophageal carcinoma and risk factors for recurrence

Table 4 Univariate analysis

Factors	Recurrence group (n = 33)	Non-recurrence group (n = 45)	t /χ2	P value
Gender			2.792	0.095
Male (n = 44)	15 (45.45)	29 (64.44)
Female (n = 34)	18 (54.55)	16 (35.56)
Age (yr)			0.179	0.672
≥ 60 (n = 38)	17 (51.52)	21 (46.67)
< 60 (n = 40)	16 (48.48)	24 (53.33)
Smoking history			0.694	0.405
Yes (n=43)	20 (60.61)	23 (51.11)
No (n=35)	13 (39.39)	22 (48.89)
History of alcoholism			1.319	0.251
Yes (n=14)	4 (12.12)	10 (22.22)
No (n=64)	29 (87.88)	35 (77.78)
Lesion location			0.602	0.740
The upper thoracic area (n = 19)	7 (21.21)	12 (26.67)
The middle thoracic area (n = 34)	16 (48.49)	18 (40.00)
The lower thoracic area (n = 25)	10 (30.30)	15 (33.33)
Tumor size			7.648	0.006
≥ 3 cm (n = 45)	25 (75.76)	20 (44.44)
< 3 cm (n = 33)	8 (24.24)	25 (55.56)
Differentiation			7.093	0.008
Low differentiation (n = 25)	16 (48.48)	9 (20.00)
Moderate + high differentiation (n = 53)	17 (51.52)	36 (80.00)
TNM staging			6.825	0.009
Stage I (n = 27)	6 (18.18)	21 (46.67)
Stage II + III (n = 51)	27 (81.82)	24 (53.33)
Adjuvant therapy			0.946	0.331
Chemotherapy (n = 52)	24 (72.73)	28 (62.22)
Radiotherapy (n = 26)	9 (27.27)	17 (37.78)
Expression of miR-1304			8.877	0.003
High expression (n = 39)	23 (69.70)	16 (35.56)
Low expression (n = 39)	10 (30.30)	29 (64.44)