Validation and evaluation of clinical prediction systems for first and repeated transarterial chemoembolization in unresectable hepatocellular carcinoma: A Chinese multicenter retrospective study

Table 2 Baseline characteristics of patients treated with first TACE and before repeated TACE, n (%) / Median [IQR]

Characteristics	Study cohort
	TACE (n = 1107)	Re-TACE (n = 912)
Gender
Male	971 (87.7)	801 (87.8)
Female	136 (12.3)	111 (12.2)
Age (year)	57 [47-65]	57 [47-65]
Etiology
HBV	1004 (90.7)	832 (91.2)
Non-HBV	103 (9.3)	80 (8.8)
Largest tumor diameter, cm
≤ 7	459 (41.5)	389 (42.7)
> 7-≤ 10	309 (27.9)	247 (27.1)
> 10	339 (30.6)	276 (30.2)
Number of tumors
1	556 (50.2)	444 (48.7)
2	244 (22.0)	212 (23.2)
≥ 3	307 (27.7)	256 (28.1)
Alpha-fetoprotein, ng/mL
< 400	626 (56.5)	523 (57.3)
≥ 400	481 (43.5)	389 (42.7)
Child-Pugh score
A5	823 (74.3)	688 (75.4)
A6	217 (19.6)	174 (19.1)
B7	67 (6.1)	50 (5.5)
ECOG score
0	639 (57.7)	529 (58.0)
1	468 (42.3)	383 (42.0)
White blood cells, 109/L	5.9 [4.4-8.2]	5.7 [4.3-7.5]
Platelets, 109/L	140 [95-199]	140 [94-197]
International normalized ratio	1.1 [1-1.1]	1.1 [1-1.1]
Alanine aminotransferase, U/L	46 [28-57]	45 [28-59]
Aspartate aminotransferase, U/L	50 [34-73]	50 [34-72]
Albumin, g/L	39.4 [36.1-43.2]	39.5 [36.2-43.3]
Total bilirubin, μmol/L	16.4 [12.0-22.9]	16.3 [12.0-22.4]
Blood urea nitrogen, mmol/L	5.6 [4.6-6.2]	5.6 [4.5-6.3]
Serum creatinine, μmol/L	72 [63-83]	72 [63-83]
Sessions of TACE	3 [2-4]	3 [2-4]

TACE: Transarterial chemoembolization; re-TACE: Repeated TACE; HBV: Hepatitis B virus; ECOG: Eastern Cooperative Oncology Group.