Impact of colorectal cancer screening participation in remote northern Canada: A retrospective cohort study

Table 3 Demographics and outcomes of screen eligible vs symptomatic individuals

Baseline characteristics	FIT eligible (n = 390)	Symptomatic (n = 288)	P value
Age, mean years (SD)	60.15 (6.55)	61.18 (6.82)	0.04741
Sex, female, n (%; Std. Res)	157 (40.26; -0.52)	127 (44.10; 0.58)	0.316
Indigenous, n (%; Std. Res)	152 (38.97; -2.15)	162 (56.25; 2.49)	0.000008
Region of residence, n (%; Std. Res)			0.0092
Beaufort Delta	42 (10.77; -0.26)	34 (11.81; 0.30)
Dehcho	17 (4.36; -0.58)	17 (5.90; 0.67)
Fort Smith	26 (6.67; -1.62)	36 (12.50; 1.88)
Hay River	39 (10.00; -0.80)	38 (13.19; 0.93)
Sahtu	21 (5.38; 0.06)	15 (5.21; -0.08)
Tilcho	18 (4.62; -0.94)	21 (7.29; 1.09)
Yellowknife	227 (58.20; 1.64)	127 (44.10; -1.91)
Size of health centre, n (%; Std. Res)			0.0002
Yellowknife	219 (56.15; 1.94)	115(39.93; -2.26)
Regional
Fort Smith	26 (6.67; -1.62)	36 (12.50; 1.88)
Hay River	36 (9.23; -0.84)	36 (12.50; 0.98)
Inuvik	21(5.38; 0.60)	11(3.82; -0.70)
Small community	88 (22.56; -1.42)	90 (31.25; 1.66)
Colonoscopy, n (%)	333 (85.38)	212 (74.65)	0.29
Completed, n (%; Std. Res)	318 (95.50; 0.15)	198 (93.40; -0.19)
Incomplete, n (%; Std. Res)	15 (4.50; -0.65)	14 (6.60; 0.81)
FIT to colonoscopy, d
Mean	159.9	183.4	0.011
Median	149.0	199.5	0.02
< 60 d, n (%; Std. Res)	79 (23.87; 0.88)	38 (18.10; -1.10)
60-180 d, n (%; Std. Res)	111 (33.53; 0.69)	59 (28.10; -0.86)	0.04
> 180 d, n (%; Std. Res)	141 (42.60; -1.16)	113 (53.80; 1.45)	0.011
Findings, n (%; Std. Res)
Low risk adenoma	99 (29.73; 1.17)	45 (21.23; -1.47)	0.03
High risk adenoma	130 (39.03; 1.41)	58 (27.36; -1.77)	0.005
Advanced adenoma	65 (19.52; 0.18)	39 (18.40; -0.23)	0.75
Cancer	13 (3.90; -1.60)	20 (9.43; 2.00)	0.008
Advanced neoplasia	78 (23.42; -0.62)	59 (27.83; 0.78)	0.25

¹Welch two sample t-test.

²Not specific to region. Std. Res: Standardized residual; SD: Standard deviation; FIT: Fecal immunohistochemical test.