Untargeted metabolomics characteristics of nonobese nonalcoholic fatty liver disease induced by high-temperature-processed feed in Sprague-Dawley rats

Figure 3 Hematoxylin-eosin staining and histology score of rat liver in the three groups. A: Steatosis of rat liver in the three groups at week 12. Scale bars = 100 μm (top row). Scale bars = 50 μm (bottom row); B: Special pathological features of rat liver from dry-fried soybeans (DFS) group at week 12 (diffuse steatosis around the portal area, scale bars = 2.5 μm. Inflammation, hepatocyte ballooning and clusters of myofibroblasts, scale bars = 50 μm); C: Histology score of steatosis, hepatocyte ballooning, lobular inflammation and nonalcoholic fatty liver disease activity score were quantified. Data are shown as mean ± standard deviation (^bP < 0.05, DFS group vs control group, nonfried soybeans group [NDFS]). H and E: Hematoxylin-eosin.