Contrast-enhanced ultrasound in association with serum biomarkers for differentiating combined hepatocellular-cholangiocarcinoma from hepatocellular carcinoma and intrahepatic cholangiocarcinoma

doi:10.3748/wjg.v26.i46.7325

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Dec 14, 2020; 26(46): 7325-7337
Published online Dec 14, 2020. doi: 10.3748/wjg.v26.i46.7325

Table 5 Diagnostic test results and modified positive predictive value and negative predictive value according to reported combined hepatocellular-cholangiocarcinoma prevalence

CHC prevalence, %	AUC	Sensitivity	Specificity	PPV	NPV	Accuracy
26.1% (35/134)	0.649	40.0	89.9	58.3	80.9	76.9
0.4%[1,13]				1.6	99.7
14.2%[2,3]				9.6	90.1

AUC: Area under the curve; CHC: Combined hepatocellular-cholangiocarcinoma; NPV: Negative predictive value; PPV: Positive predictive value.

Citation: Yang J, Zhang YH, Li JW, Shi YY, Huang JY, Luo Y, Liu JB, Lu Q. Contrast-enhanced ultrasound in association with serum biomarkers for differentiating combined hepatocellular-cholangiocarcinoma from hepatocellular carcinoma and intrahepatic cholangiocarcinoma. World J Gastroenterol 2020; 26(46): 7325-7337
URL: https://www.wjgnet.com/1007-9327/full/v26/i46/7325.htm
DOI: https://dx.doi.org/10.3748/wjg.v26.i46.7325