Altered metabolism of bile acids correlates with clinical parameters and the gut microbiota in patients with diarrhea-predominant irritable bowel syndrome

Figure 1 Correlations between fecal bile acids and clinical parameters in patients with diarrhea-predominant irritable bowel syndrome. A-D: Defecation frequency was positively correlated with the level of cholic acid and chenodeoxycholic acid (CDCA), and negatively correlated with the level of deoxycholic acid and lithocholic acid; E: The first sensation threshold was negatively correlated with CDCA; F: The defecating sensation threshold tended to be negatively correlated with CDCA. CA: Cholic acid; CDCA: Chenodeoxycholic acid; DCA: Deoxycholic acid; LCA: Lithocholic acid.