Lactobacillus bulgaricus inhibits colitis-associated cancer via a negative regulation of intestinal inflammation in azoxymethane/dextran sodium sulfate model

Figure 4 Lactobacillus bulgaricus regulates the production of tumors proinflammatory cytokines in azoxymethene/dextran sulfate sodium-exposed mice. Tumor tissues were homogenized and the concentration of TNF-α, IL-6, IL- 1β, IL-17, IFN-γ e IL-23 per gram of tissue (colon) were determined by ELISA (n = 10 mice per group). Results expressed as mean ± SEM. ^aP < 0.05, ^bP < 0.01, ^eP < 0.001 vs controls. Ctrl: Controls; Lb: Lactobacillus bulgaricus.