Feasibility and nutritional impact of laparoscopic assisted tailored subtotal gastrectomy for middle-third gastric cancer

Table 6 Univariate and multivariate analyses of disease free survival for included patients

Variable	Univariate	P value	Multivariate	P value
	HR (95%CI)		HR (95%CI)
Age, yr (≤ 65)	0.505 (0.209-1.221)	0.129	-	-
Sex (female)	0.795 (0.288-2.192)	0.658	-	-
BMI (≤ 25 kg/m2)	0.675 (0.259-1.761)	0.422		-
ASA (I/II/III)	1.864 (0.277-12.523)	0.522	-	-
Previous abdominal operation	0.045 (0.000-188.621)	0.467	-	-
Primary Site (L/M/LM)	0.993 (0.715-1.377)	0.964	-	-
Tumor size, (> 4 cm)	2.535 (1.035-6.208)	0.042	1.740 (0.706- 4.294)	0.229
Neoadjuvant chemotherapy (Yes)	1.338 (0.442-4.051)	0.606	-	-
Tumor grade (W/M/P/U)	0.852 (0.580-1.252)	0.416	-	-
Lauren classification (I/D/M)	0.970 (0.523-1.798)	0.923	-	-
pTNM stage (I/II/III)	3.317 (1.566-7.023)	0.002	3.353 (1.558-7.214)	0.002
Lymphovascular invasion (Yes)	2.209 (0.906-5.383)	0.081	-	-
Neural infiltration (Yes)	1.729 (0.703-4.253)	0.233	-	-
Surgical type (LaTSG/LaTG)	2.859 (1.027-7.958)	0.044	2.776 (0.981-7.854)	0.054
Operation time (> 210 min)	1.115 (0.450-2.761)	0.814	-	-
Estimated blood loss (> 200 mL)	1.273 (0.526-3.080)	0.592	-	-
Intraoperative blood transfusion (Yes)	0.938 (0.274-3.208)	0.919	-	-
No. of retrieved lymph nodes (> 30)	1.643 (0.593-4.553)	0.339	-	-
Proximal margin (> 3 cm)	0.904 (0.373-2.192)	0.823	-	-
Distal margin (> 3 cm)	0.537 (0.219-1.319)	0.175	-	-

BMI: Body mass index; ASA: American Society of Anesthesiologists; L: Lesser curve; M: Middle; ML: Middle and low; W: Well differentiated; M: Moderately differentiated; P: Poorly differentiated; U: Undifferentiated; I: Intestinal type; D: Diffuse type; M: Mixed type; LaTSG: Laparoscopic assisted tailored subtotal gastrectomy; LaTG: Laparoscopic assisted total gastrectomy.