Feasibility and nutritional impact of laparoscopic assisted tailored subtotal gastrectomy for middle-third gastric cancer

Table 5 Univariate and multivariate analyses of overall survival for included patients

Variable	Univariate	P value	Multivariate	P value
	HR (95%CI)		HR (95%CI)
Age, yr (≤ 65)	0.831 (0.301-2.293)	0.721	-	-
Sex (female)	0.493 (0.204-1.192)	0.117	-	-
BMI (≤ 25 kg/m2)	0.703 (0.270-1.832)	0.471	-	-
ASA (I/II/III)	1.440 (0.256-8.086)	0.679	-	-
Previous abdominal operation	0.046 (0.000-250.286)	0.482	-	-
Primary site (L/M/LM)	0.981 (0.707-1.360)	0.908	-	-
Tumor size (> 4 cm)	2.607 (1.064-6.390)	0.036	1.180 (0.906-1.538)	0.219
Neoadjuvant chemotherapy (Yes)	1.369 (0.454-4,129)	0.577	-	-
Tumor grade (W/M/P/U)	0.851 (0.578-1.253)	0.415	-	-
Lauren classification (I/D/M)	0.949 (0.513-1.758)	0.869	-	-
pTNM stage (I/II/III)	3.195 (1.518-6.724)	0.002	3.170 (1.461-6.878)	0.004
Lymphovascular invasion (Yes)	2.203 (0.906-5.358)	0.081	-	-
Neural infiltration (Yes)	1.755 (0.715-4.304)	0.219	-	-
Surgical type (LaTSG/LaTG)	2.977 (1.073-8.263)	0.036	2.876 (1.009-8.195)	0.048
Operation time (> 210 min)	1.130 (0.456-2.803)	0.791	-	-
Estimated blood loss (> 200 mL)	1.261 (0.522-3.048)	0.606	-	-
Intraoperative blood transfusion (Yes)	0.933 (0.273-3.192)	0.912	-	-
No. of retrieved lymph nodes (> 30)	1.631 (0.590-4.511)	0.346	-	-
Proximal margin (> 3 cm)	0.876 (0.362-2.120)	0.770	-	-
Distal margin (> 3 cm)	0.500 (0.203-1.121)	0.132	-	-

BMI: Body mass index; ASA: American Society of Anesthesiologists; L: Lesser curve; M: Middle; ML: Middle and low; W: Well differentiated; M: Moderately differentiated; P: Poorly differentiated; U: Undifferentiated; I: Intestinal type; D: Diffuse type; M: Mixed type; LaTSG: Laparoscopic-assisted tailored subtotal gastrectomy; LaTG: Laparoscopic assisted total gastrectomy.