Associations of content and gene polymorphism of macrophage inhibitory factor-1 and chronic hepatitis C virus infection

Table 2 Genotypes and allele distribution in subjects

Genotype	Control group, n = 82	CHC group, n = 178	χ2	P value	P value1	OR value (95%CI)
rs1059369 gene
AA	32 (0.390)	58 (0.326)	4.142	0.126	0.252
AT	42 (0.512)	85 (0.478)
TT	8 (0.098)	35 (0.197)
A	106 (0.646)	201 (0.565)	3.102	0.078	0.156	0.710 (0.484-1.040)
T	58 (0.354)	155 (0.435)
Het	0.4574	0.4916
PIC	0.3528	0.3707
rs1059519 gene
CC	16 (0.195)	17 (0.096)	7.191	0.028	0.056
CG	33 (0.402)	63 (0.354)
GG	33 (0.402)	98 (0.551)
C	65 (0.396)	97 (0.272)	8.032	0.004	0.008	0.570 (0.386-0.843)
G	99 (0.604)	259 (0.728)
Het	0.4784	0.396
PIC	0.364	0.3176
Haplotype
AC	65.00 (0.396)	97.00 (0.272)	8.033	0.005		0.570 (0.386-0.843)
AG	41.00 (0.250)	104.00 (0.292)	0.991	0.319		1.238 (0.813-1.886)
TG	58.00 (0.354)	155.00 (0.435)	3.102	0.078		1.409 (0.961-2.066)
TC	0.00 (0.000)	0.00 (0.000)

¹P values were adjusted by Bonferroni correction; P < 0.05 indicates statistical significance. CHC: Chronic hepatitis C; Het: Heterozygosity; OR: Odds ratio; PIC: Polymorphic information content.