Focus on gastroesophageal reflux disease in patients with cystic fibrosis

Table 5 Impact of gastroesophageal reflux disease on pulmonary disease

Ref.	Year	N pts	Median age (yr)	Pts With GERD (%)	N pts with FEV1 > 90%	N pts with FEV1 70%-89%	N pts with FEV1 40%-69%	N pts with FEV1 < 40%	P value Reflux on; Pulmonary function
Gustaffson et al[3]	1991	12	14.4	66	4	2	4	2	P < 0.05
Stringer et al[40]	1988	57	21.6	31	ND	ND	ND	ND	P < 0.01

N: Number; pts: Patients; GERD: Gastroesophageal reflux disease; FEV1: Forced expiratory volume in 1 second l.