New strain of Pediococcus pentosaceus alleviates ethanol-induced liver injury by modulating the gut microbiota and short-chain fatty acid metabolism

Figure 7 Correlation network analysis of representative microbial genera, gut barrier markers, inflammatory cytokines and liver injury-related indices. Spearman’s correlation analysis was performed, and statistical significance was indicated as follows: ^aP < 0.05, ^bP < 0.01, ^cP < 0.001. TLR4: Toll-like receptor 4; IL: Interleukin; MIP-1α: Macrophage inflammatory protein-1α; ALT: Alanine aminotransferase; AST: Aspartate transaminase; TNF-α: Tumor necrosis factor-α; KC: Keratinocyte-derived protein chemokine; G-CSF: Granulocyte colony-stimulating factor; MUC: Mucin; LBP: Lipopolysaccharide-binding protein.