Dynamic contrast-enhanced magnetic resonance imaging and diffusion-weighted imaging in the activity staging of terminal ileum Crohn's disease

Figure 2 A 42-year-old male with remission of Crohn’s disease in the terminal ileum and a Crohn’s Disease Activity Index of 108 and Crohn’s Disease Endoscopic Index of Severity of 2. A: Axial T2-weighted image shows mural thickening and hyperintensity in the terminal ileum (arrow); B: Axial diffusion-weighted imaging image (b = 800 s/mm²) demonstrates high signal (arrow) in the same bowel segment. Regions of interest (ROI) for the inflammatory bowel wall shows that apparent diffusion coefficient = 1.89×10^-3 mm²/s; C: K^trans map is obtained through the relevant phase. The perfusion parameters of the ROI placed in the terminal ileum is calculated by TCM (K^trans = 0.18 min^-1); D: K_ep map is obtained through the relevant phase. The K_ep of the ROI placed is 0.98 min^-1; E: V_e map is obtained through the relevant phase. The V_e of the ROI placed is 0.19; F: The contrast concentration curve is plotted as ROI (line with circle) and fitted with the model (line). ROI: Region of interest.