Dynamic contrast-enhanced magnetic resonance imaging and diffusion-weighted imaging in the activity staging of terminal ileum Crohn's disease

Table 2 Parameters in the normal ileal loop and the inflamed terminal ileum in different staging of Crohn’s disease

Parameter	Total				Remission CD			Mild CD			Moderate-severe CD
	NIL	ITI	P value		NIL	ITI	P value	NIL	ITI	P value	NIL	ITI	P value
Ktrans (min -1)	0.01 ± 0.01	0.07 ± 0.04	< 0.001		0.01 ± 0.01	0.03 ± 0.01	< 0.001	0.01 ± 0.00	0.05 ± 0.01	< 0.001	0.01 ± 0.00	0.12 ± 0.04	< 0.001
Kep (min -1)	0.15 ± 0.05	0.24 ± 0.11	< 0.001		0.11 ± 0.03	0.16 ± 0.05	< 0.001	0.18 ± 0.05	0.21 ± 0.05	< 0.001	0.15 ± 0.05	0.35 ± 0.11	< 0.001
Ve	0.08 ± 0.03	0.27 ± 0.07	< 0.001		0.10 ± 0.04	0.18 ± 0.03	< 0.001	0.07 ± 0.02	0.26 ± 0.03	< 0.001	0.08 ± 0.03	0.35 ± 0.05	< 0.001
ADC (×10-3 mm2/s)	2.41 ± 0.30	1.41 ± 0.26	< 0.001		2.33 ± 0.26	1.72 ± 0.12	< 0.001	2.45 ± 0.31	1.42 ± 0.12	< 0.001	2.42 ± 0.30	1.12 ± 1.12	< 0.001
MaRIA		14.10 ± 10.09				6.39 ± 1.07			9.34 ± 1.30			27.12 ± 8.23

NIL: Normal ileal loop; ITI: Inflamed terminal ileum; CD: Crohn’s disease; ADC: Apparent diffusion coefficient; MaRIA: Magnetic Resonance Index of Activity.