Identification of differentially expressed genes in ulcerative colitis and verification in a colitis mouse model by bioinformatics analyses

Table 4 Enriched terms in the Kyoto Encyclopedia of Genes and Genomes pathways for differentially expressed genes identified in ulcerative colitis (P < 0.05)

Pathway ID	Term	Genes
hsa04062	Chemokine signaling pathway	CXCL1, FGR, CXCL5, CXCL3, CXCL2, CXCL9, CXCR2, CXCL6, CXCL11, CCL18, CXCL10, CXCL13, JAK3.
hsa04060	Cytokine-cytokine receptor interaction	CXCL1, CXCL5, CXCL3, CXCL2, CXCL9, CXCR2, CXCL6, IL24, CXCL11, CCL18, CXCL10, CXCL13, CSF3R, IL1B.
hsa04610	Complement and coagulation cascades	CR1, C3, CFB, C4BPB, SERPINA1, CFI.
hsa04514	Cell adhesion molecules	SELP, SELL, CD274, CTLA4, CLDN2, CDH3.
hsa00830	Retinol metabolism	CYP2B6, ADH1C, UGT2A3.
hsa00980	Metabolism of xenobiotics by cytochrome P450	CYP2B6, ADH1C, UGT2A3.
hsa04620	Toll-like receptor signaling pathway	CXCL9, IL1B, CXCL11, SPP1, CXCL10.
hsa00982	Drug metabolism	CYP2B6, ADH1C, UGT2A3.
hsa03320	PPAR signaling pathway	HMGCS2, AQP7, PCK1.

PPAR: Peroxisome proliferator-activated receptor.