Risk prediction rule for advanced neoplasia on screening colonoscopy for average-risk individuals

doi:10.3748/wjg.v26.i37.5705

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Oct 7, 2020; 26(37): 5705-5717
Published online Oct 7, 2020. doi: 10.3748/wjg.v26.i37.5705

Table 1 Univariate analysis of clinical features and detection of advanced neoplasia

Characteristic	Total	Absence of AN	Presence of AN	P value
	n (%)	n (%)	n (%)
Age (mean ± SD)	980 (100)	61 ± 8	63 ± 9	0.242
Median, IQR		60, 12	63, 13
Male	479 (48.9)	448 (48.2)	31(62.0)	0.07
Smoking	460 (46.9)	425 (45.7)	35 (70.0)	0.01
Daily bowel movement	859 (87.7)	814 (87.6)	45 (90.0)	0.62
Caffeine	885 (90.3)	836 (89.9)	49 (98.0)	0.06
Exercise	544 (55.5)	52 (56.5)	19 (38.0)	0.01
Alcohol	491 (50.1)	468 (50.3)	23 (46.0)	0.55
Daily red meat consumption	90 (9.2)	81 (8.7)	9 (18.0)	0.03
Daily poultry consumption	39 (4.0)	37 (4.0)	2 (4.0)	0.99
Daily dairy consumption	744 (75.9)	703 (75.6)	41 (82.0)	0.30
Daily fruit/vegetable consumption	909 (92.8)	865 (93.0)	44 (88.0)	0.18
NSAID use	177 (18.1)	171 (18.4)	6 (12.0)	1.31
Aspirin use	312 (31.8)	294 (31.6)	18 (36.0)	0.42
Multi vitamin/antixoidant use	415 (42.3)	397 (42.7)	18 (36.0)	0.87
Oral contraceptive pills/hormone replacement therapy used	126 (12.9)	121 (13.0)	5 (10.0)	0.38
Calcium supplementation	429 (43.8)	413 (44.4)	16 (32.0)	0.30
Diabetes mellitus	80 (8.2)	74 (8.0)	6 (12.0)	1.04
Body Mass Index (BMI)				0.01
mean ± SD	980 (100)	26.7 ± 4.1	28.4 ± 3.3	0.01
Median, IQR		26.7, 5.1	28.5, 4.5
< 25^a	330 (33.7)	322 (34.6)	8 (16.0)
25-30	454 (46.3)	429 (46.1)	25 (50.0)
> 30^a	196 (20.0)	179 (19.2)	17 (34.0)
Pack years				< 0.01
mean ± SD	980 (100)	13 ± 21	29 ± 33	< 0.01
Median, IQR		0, 20	18, 40
≤ 10^a	520 (53.1)	505 (54.3)	15 (30.0)
11-40^a	331 (33.8)	311 (33.4)	20 (40.0)
> 40^a	129 (13.2)	114 (12.3)	15 (30.0)
Frequency of alcohol intake				0.8
None	489 (49.9)	462 (49.7)	27 (54.0)
< 1 drink daily	391 (39.9)	377 (40.5)	14 (28.0)
At least 1 drink daily	100 (10.2)	91 (9.8)	9 (18.0)
Daily alcohol consumption	100 (10.2)	91 (9.8)	9 (18.0)	0.06
Body surface area (mean ± SD)		1.8 ± 2.045	1.9 ± 0.02	0.02
Median, IQR		1.8, 0.28	1.9, 0.22

^aIndicates significance on post-hoc analysis (P < 0.05), AN: Advanced neoplasia.

Citation: Sharara AI, El Mokahal A, Harb AH, Khalaf N, Sarkis FS, M El-Halabi M, Mansour NM, Malli A, Habib R. Risk prediction rule for advanced neoplasia on screening colonoscopy for average-risk individuals. World J Gastroenterol 2020; 26(37): 5705-5717
URL: https://www.wjgnet.com/1007-9327/full/v26/i37/5705.htm
DOI: https://dx.doi.org/10.3748/wjg.v26.i37.5705