Endoscopic ultrasound-fine needle biopsies of pancreatic lesions: Prospective study of histology quality using Franseen needle

Table 3 Technical characteristics and outcomes of endoscopic ultrasound-fine needle biopsies

Parameter	Value
Needle passes/patient, n (%)	2 (100)
Acquired histology, n (%)	40 (100)
Immunhistochemistry, n (%)	12 (30)
Histologic quality (Payne score), n (%)
Score 0 (needle pass 1/needle pass 2/overall)	1 (2.5)/1 (2.5)/1 (2.5)
Score 1 (needle pass 1/needle pass 2/overall)	2 (5)/3 (7.5)/1 (2.5)
Score 2 (needle pass 1/needle pass 2/overall)	3 (7.5)/3 (7.5)/1 (2,5)
Score 3 (needle pass 1/needle pass 2/overall)	34 (85)/33 (82.5)/37 (92.5)
Histologic quality, median (range)	2.85 (0-3)
Acquired high quality histology1, n (%)
Needle pass 1/needle pass 2/overall	34 (85)/33 (82.5)/37 (92.5)
Length of the biopsy cylinder (mm), mean (SD)
Needle pass 1/needle pass 2/overall	1.56 (0.9)/1.5 (0.9)/1.54 (0.9)
Diameter of the biopsy cylinder (mm), mean (SD)
Needle pass 1/needle pass 2/overall	0.41 (0.1)/0.38 (0.1)/0.39 (0.1)
Diagnostic accuracy	85%2/89.2%3
Sensitivity	78%
Specificity	100%
Positive predictive value	100%
Negative predictive value	53%
Complications, n (%)	1 (2.5)4

¹Defined as Payne score 3.

²In all patients (n = 40).

³In patients with an available high quality (Payne score 3) histological specimen (n = 37).

⁴self-limiting bleeding at puncture site.