Helicobacter pylori infection with atrophic gastritis: An independent risk factor for colorectal adenomas

Table 5 Association between Helicobacter pylori infection, atrophic gastritis and colorectal neoplasm

	HP (–) AG (–), n = 2758		HP (–) AG (+), n = 279			HP (+) AG (–), n = 2658			HP (+) AG (+), n = 323
	n (%)	OR (95%CI)	n (%)	OR (95%CI)	P value	n (%)	OR (95%CI)	P	n (%)	OR (95%CI)		P
Age in yr, mean ± SD	47.7 ± 10.6		52.8 ± 10.5			47.5 ± 10.1			52.3 ± 9.8
Male sex	1818 (65.9)		193 (69.2)			1677 (63.1)			216 (66.9)
Nonadenomatous polyp	460 (16.7)	1	54 (19.4)	1.339 (0.969-1.851)	0.077	447 (16.8)	1.043 (0.901-1.206)	0.574	62 (19.2)	1.394 (1.027-1.892)		0.033
Adenoma	416 (15.1)	1	60 (21.5)	1.645 (1.202-2.252)	0.002	457 (17.2)	1.179 (1.017-1.367)	0.029	79 (24.5)	1.964 (1.477-2.610)		< 0.001
Advanced adenoma	58 (2.1)	1	7 (2.5)	1.377 (0.618-3.064)	0.434	64 (2.4)	1.184 (0.825-1.699)	0.360	14 (4.3)	2.496 (1.366-4.562)		0.003

Univariate logistic regression was used to analyze the association between Helicobacter pylori infection, atrophic gastritis and colorectal neoplasm. HP: Helicobacter pylori; AG: Atrophic gastritis; OR: Odds ratio; CI: Confidence interval; SD: Standard deviation.